De La Renta, who most recently designed Amal Clooney's wedding dress, was diagnosed with cancer in 2006.
Born in the Dominican Republic in 1932, he left home at 18 to study painting in Madrid, Spain.
He soon developed a love of fashion design and began an apprenticeship with Spain's designer Cristobal Balenciaga.
De la Renta made his name in the early 1960s when the then first lady, Jackie Kennedy, frequently wore his designs. He launched his own label several years later.
Over the following decades he dressed nearly every first lady up to and including Michelle Obama, who he once chided for not wearing American designers.
Mo Abudu adores Oscar De La Renta outfits.
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